Lipopolysaccharide Structure and Biosynthesis in H elicobacter pylori
نویسندگان
چکیده
منابع مشابه
Challenges in Diagnosis of H. Pylori Infection in Children
H. pylori infection is usually acquired in early childhood. Its role in gastrointestinal and extra intestinal complaints and serious consequences in adulthood make it as challenging issues. Despite different clinical presentations, in most children, the presence of H. pylori infection does not lead to clinically apparent disease, even when it causes chronic active gastritis. Some of most import...
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Helicobacter pylori NCTC 11637 lipopolysaccharide (LPS) expresses the human blood group antigens Lewis x (Le(x)), Le(y), and H type I. In this report, we demonstrate that the H type I epitope displays high-frequency phase variation. One variant expressed Le(x) and Le(y) and no H type I as determined by serology; this switch was reversible. Insertional mutagenesis in NCTC 11637 of JHP563 (a poly...
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SARS CoV-2 and H. pylori are pathogens associated with the most common viral and bacterial infections globally. The co-infection of pathogenic bacteria and SARS CoV-2 represented a true health challenge. The current study aimed to estimate the incidence of H. pylori in patients with COVID-19. For this purpose, 130 patients with RT-PCR confirmed SARS CoV-2 infection as well as 130 apparently he...
متن کاملPhase variation in Helicobacter pylori lipopolysaccharide.
Helicobacter pylori NCTC 11637 lipopolysaccharide (LPS) expresses the human blood group antigen Lewis x (Le(x)) in a polymeric form. Le(x) is beta-D-galactose-(1-4)-[alpha-L-fucose-(1-3)]-beta-D-acetylglucosamine. Schematically the LPS structure is (Le(x))n-core-lipid A. In this report, we show that Le(x) expression is not a stable trait but that LPS displays a high frequency (0.2 to 0.5%) of p...
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BACKGROUND Mycobacteria produce two unique families of cytoplasmic polymethylated polysaccharides -- the methylglucose lipopolysaccharides (MGLPs) and the methylmannose polysaccharides (MMPs) -- the physiological functions of which are still poorly defined. Towards defining the roles of these polysaccharides in mycobacterial physiology, we generated knock-out mutations of genes in their putativ...
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ژورنال
عنوان ژورنال: Helicobacter
سال: 2016
ISSN: 1083-4389,1523-5378
DOI: 10.1111/hel.12301